utility (Applications > Utilities) to see if the device appears in the "MIDI Studio" window. If it’s grayed out, the driver is likely not loading. Apple Discussions step-by-step instructions
If you have an older Mac dedicated to music production, you can use the final official driver. This is not recommended for your primary internet-connected machine.
This guide will show you exactly how to get your Radium 49 working on a modern Mac, whether you need legacy drivers or, as is often the case, no drivers at all. Does the M-Audio Radium 49 Need a Driver on Mac?
This means you do need to install old drivers from the M-Audio legacy website to get the keys and faders to communicate with modern DAW software like GarageBand, Logic Pro, or Ableton Live.
The Ultimate Guide to M-Audio Radium 49 Drivers on Mac The M-Audio Radium 49 is a classic 49-key MIDI controller. It features eight assignable knobs and eight assignable sliders. Many musicians still love its lightweight design and tactile control. However, getting this legacy hardware to work on modern macOS versions can be challenging.
: The most reliable way to use this keyboard today is to bypass its built-in USB port. Connect a standard MIDI cable from the MIDI Out port on the back of the Radium 49 to a modern, class-compliant USB MIDI Interface.