Outside of internet philosophy, the term "blue pill" has an incredibly prominent medical definition. It is the global universal nickname for Viagra (Sildenafil) , the revolutionary medication that transformed men’s health and broke the taboo surrounding erectile dysfunction (ED).
To understand the online discourse surrounding "blue pill men," one must look at the metaphorical origins from The Matrix . In the film, taking the blue pill allows a person to remain in a comfortable, unquestioned illusion. bluepillmen.com