Is AutoCAD 2022 still using the "Serial Number + Product Key" method, or has it moved entirely to the activation?

I can guide you through the exact setup steps for your environment.

: After launching the software, select Enter a Serial Number on the "Let's Get Started" screen to input your credentials .

There are several legitimate avenues to obtain a serial number and license for AutoCAD 2022. Autodesk actively encourages users to uninstall any nonvalid software and acquire a genuine license.